The Male Sex Drive — How it Changes With Age

Published on July 24, 2023 .
Kristopher Bunting, MD  Author

This article is a repost which originally appeared on healthnews

Edited for content. The opinions expressed in this article may not reflect the opinions of this site’s editors, staff or members.

For many men, having a strong sex drive—or libido—can be an important part of feeling healthy and having a good quality of life.

Key takeaways:

‧ Male sex drive and testosterone levels decrease with age.

‧ Less sex does not mean less sexual satisfaction.

‧ Good health improves sexual function and sexual quality of life at any age.

‧ Aerobic exercise can improve sexual function and sexual satisfaction.

However, as men age and their bodies change, so does their sex drive. Sex drive tends to decrease with age after it peaks in men in their 20s, but that does not mean that aging has to have a negative effect on sex.

Age, sex drive, and sexual satisfaction

Most men (and women) are more sexually active in their 20s than in any other decade of life. Men’s sex drives seem to peak in their 20s and begin to decrease in their 30s and onward slowly. Men in their 40s and older are also more likely to have problems with sexual function, including erectile dysfunction.

Men have less sex as they get older, but that is only half the story. Sexual satisfaction does not necessarily decrease with age.

A study in Norway found that although sexual activity decreases with age and sexual dysfunction increases with age, sexual satisfaction is more complex. According to the study, men in their 20s had the highest level of sexual satisfaction, followed by men in their 50s. Surprisingly, despite increased sexual dysfunction and decreased sex drive, men in their 50s reported higher sexual satisfaction than those in their 30s and 40s.

Another study from the US found that overall, sexual quality of life tended to decrease with age but was higher in older people who had a better quality of sex. The authors attributed this to “sexual wisdom”—better sex through past experience. No matter the cause, this is certainly good news for anyone worried about their odds of having a fulfilling sex life as they age.

Testosterone and sex drive

Testosterone levels play a major role in the male sex drive. Testosterone is the primary sex hormone responsible for male sexual development and is also associated with sex drive. Research has shown that men’s testosterone levels decline with age beginning after age 30, and reach their lowest levels after age 70—when sex drive is at its lowest.

Low testosterone in men is called male hypogonadism. Hypogonadism in men can cause or contribute to lower sex drive, erectile dysfunction, infertility, loss of bone mass, loss of muscle mass, and depression.

Testosterone replacement therapy can treat male hypogonadism, and research shows that in older men, it can improve sexual activity, sexual desire, and erectile dysfunction. In a study of men with poorly controlled type 2 diabetes, testosterone replacement therapy was shown to improve not only sexual function but also the quality of life and memory.

While considered a normal part of aging, low testosterone can be caused by various medical conditions, including head injuries and some medications. Certain prescription medications can decrease testosterone levels, including opioids (painkillers), hormone therapy for prostate cancer, and a few other drugs.

Remember, do not stop taking any medication without first talking with your healthcare provider. If you are concerned about your testosterone levels, discuss it with your doctor or another healthcare provider.

Better health means better sex

As men age, health plays an increasingly important role in their sex life. According to research, people in better health are more interested in sex, have sex more often, and have a better sexual quality of life. On the other hand, high blood pressure, heart disease, and other conditions that affect blood flow can affect sex drive and contribute to male sexual dysfunction.

Medications can also affect sex drive and sexual performance in men, including some prescription medications for high blood pressure, depression, prostate disease, and hair loss. Common medications that contribute to low sex drive and sexual dysfunction are beta-blockers, diuretics, and finasteride (Propecia, Proscar). Always discuss possible medication side effects with your healthcare provider—the benefits may outweigh the drawbacks.

Erectile dysfunction

Along with a decreased sex drive, aging, poor health, and certain medications can also lead to erectile dysfunction—a known contributor to depression. Fortunately, modern medicine has dedicated a great deal of research to improving men’s erections.

Nowadays, there are several ways to successfully improve erectile dysfunction, including penile implants and medications such as sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra, Staxn). While these medications are safe for many men, they can cause dangerous side effects in people taking nitrates (such as nitroglycerin, isosorbide, and others).

However, it is possible to improve erectile function with natural means such as CBD oils. The latter is one of the best ways to reduce anxiety and stress interfering with libido. CBD oils and gummies improve blood flow in vessels, thus benefiting erectile function. Full-spectrum CBD oils are believed to be a better choice for erectile dysfunction containing both CBD and THC in moderate amounts.

Exercise can improve sex

It is no secret that aerobic exercise is good for your health. It helps reduce cholesterol, blood pressure, and body fat in addition to decreasing the risk of death from coronary artery disease. Studies also show that aerobic exercise is also important for sexual health.

A study in Japan found that regular aerobic exercise improved sexual function in men aged 43-59. Another group of researchers in the U.S. showed that aerobic exercise—running, cycling, or swimming—improved sexual function in men aged 18-50. The potential for better sex life is excellent motivation to get more exercise,

When do men stop being sexually active?

If you think that people stop being sexually active when they get older, you would be wrong. Research shows that men have a sexual life expectancy well into their 70s. While it is true that sexual activity decreases with age, even the elderly are busy getting busy.

In fact, the 55 and older population has had a significant increase in sexually transmitted diseases (STDs) over the past few decades, including chlamydia, gonorrhea, syphilis, and HIV. While an increase in STDs may be alarming, it clearly indicates that both men and women keep having sex well into old age.

As men age, they tend to have less sex but have high satisfaction with their sex life. Aging and health can have significant effects on sexual function and satisfaction, but medical treatment and exercise can improve both sexual function and sexual satisfaction at any age. If you are concerned about decreased sex drive or sexual dysfunction, talk with your healthcare provider.

Resources:

1. BJU International. Assessment of male sexual function by the Brief Sexual Function Inventory.
2. NIH. Sexual Quality of Life and Aging: A Prospective Study of a Nationally Representative Sample.
3. StatPearls. Physiology, Testosterone.
4. Endocrine Reviews. The Decline of Androgen Levels in Elderly Men and Its Clinical and Therapeutic Implications.
5. Mayo Clinic. Male hypogonadism.
6. The Journal of Clinical Endocrinology & Metabolism. Testosterone Treatment and Sexual Function in Older Men With Low Testosterone Levels.
7. ENDOCRINE SOCIETY. Testosterone improves quality of life, sexual function, and delayed verbal recall in men with uncontrolled type 2 diabetes.
8. ISSM. Can prescription medications affect testosterone levels?
9. thebmj. Sex, health, and years of sexually active life gained due to good health: evidence from two US population based cross sectional surveys of ageing.
10. NHS. Low sex drive (loss of libido).
11. Mayo Clinic. High blood pressure and sex: Overcome the challenges.
12. MedlinePlus. Finasteride.
13. NIH. Sexuality in Ageing Male: Review of Pathophysiology and Treatment Strategies for Various Male Sexual Dysfunctions.
14. NIH. Increased incidence of depressive symptoms in men with erectile dysfunction.
15. NIH. Health benefits of aerobic exercise.
16. NIH. Regular aerobic exercise improves sexual function assessed by the Aging Males’ Symptoms questionnaire in adult men.
17. NIH. Exercise Improves Self-Reported Sexual Function Among Physically Active Adults.
18. EmergencyMedicineNews. STI Rate Has Doubled Among Senior Citizens.

Nitroglycerin Gel for ED: Pros, Cons, & Practical Information

About Nitroglycerin Gel for Erectile Dysfunction

Medically reviewed by Matt Coward, MD, FACS — Written by Sara Lindberg on December 16, 2020

This article is a repost which originally appeared on Healthline

Edited for content

Erectile dysfunction (ED) may affect as many as 30 million men in the United States. People with ED experience an inability to get or keep an erection firm enough for sex.

You may be familiar with some of the more common treatments for ED, including lifestyle modifications, oral medications that include phosphodiesterase type 5 inhibitors (PED5 inhibitors), and penis pumps.

But a study published in the Journal of Sexual Medicine also looked at the use of nitroglycerin gel or cream as a topical treatment for ED. Although results look promising, it’s important to note that nitroglycerin gel or cream isn’t approved by the Food and Drug Administration (FDA) to treat ED.

Here’s what you need to know about nitroglycerin as a topical treatment for erectile dysfunction.

What is nitroglycerin?

Nitroglycerin is part of a class called vasodilators, which widen the blood vessels and improve blood flow to allow oxygen-rich blood to reach the heart.

It comes in a variety of forms, including sublingual (under-the-tongue), topical cream or gel, and as a transdermal patch. Nitroglycerin is most often used to prevent angina or attacks of chest pains.

Nitroglycerin for ED

“The idea of treating ED with topical nitroglycerin is not new and was first described in the 1980s,” says Dr. Joseph Brito, a urologist at Yale New Haven Health, Lawrence + Memorial Hospital. Brito is also a member of Healthline’s clinical review network.

In general, Brito says nitroglycerin works by dilating the blood vessels, which is why it’s traditionally used for patients with angina or chest pain due to poor cardiac vessel blood flow.

The concept is the same for ED, although Brito says it may have a dual mechanism of action:

  • It widens blood vessels helps blood flow.
  • It relaxes penile smooth muscle, which in turn compresses penile veins and impedes blood flow out of the penis, which causes rigidity.

How does nitroglycerin gel work?

According to Brito, nitroglycerin gel or cream differs from other ED treatments such as oral medications:

“[Topical nitroglycerin] acts as a nitrogen donor to increase local levels of nitric oxide, which works through molecular signaling (cGMP pathway) to cause this response,” he says.

On the other hand, Brito says PDE5 inhibitors (like tadalafil and sildenafil) work at a later step in the chain by inhibiting the breakdown of cGMP.

Nitroglycerin for ED doesn’t have enough research

That said, Brito points out that nitroglycerin gel or cream is currently not approved by the FDA to treat ED.

Moreover, Brito points out that the American Urological Association guideline on erectile dysfunction published in 2018 didn’t include topical nitroglycerin as a suggested treatment for men with ED.

“Though this therapy was not specifically mentioned, the authors did state ‘the use of these treatments may preclude the use of other treatments known to be effective,’ and felt more research was needed,” he explains.

And there’s another factor to consider: Nitroglycerin cream on the outside of the penis might be transferred to your partner.

Why are people interested nitroglycerin gel for ED?

“Nitroglycerin may have some benefits over standard oral ED medications,” Brito says.

The onset of topical nitroglycerin is between 10 and 20 minutes, which Brito says is better than the quickest acting oral agents, with sildenafil taking at least 30 minutes.

In fact, the 2018 study published in the Journal of Sexual Medicine found that 44 percent of patients saw erection beginning within 5 minutes of application. Seventy percent of the men noticed an erection within 10 minutes.

The randomized, double-blind, placebo-controlled study included 232 men with ED who participated in two 4-week trials. One trial used a 0.2 percent glyceryl trinitrate topical gel before sex, and the other used a placebo gel.

“This may help with spontaneity, which can be an issue for couples using oral agents,” Brito explains.

Another benefit, Brito says, is that unlike other ED treatments like oral agents, nitroglycerin doesn’t need to pass through the gastrointestinal (GI) tract.

“Since absorption of oral agents like sildenafil is strongly affected by food intake, the medications are much more effective when taken on an empty stomach,” he says. This requires more planning and doesn’t always allow for spontaneity.

Where to buy nitroglycerin for ED

Nitroglycerin gel or cream is currently not approved by the FDA to treat ED.

If you have questions about this topical treatment, you need to talk with a doctor who knows your medical history. A prescription is needed for nitroglycerin.

How to take nitroglycerin gel for ED

Nitroglycerin use is managed by your doctor. Don’t use or apply this topical treatment without guidance.

According to the Journal of Sexual Medicine, the concentration studied was 0.2 percent, which Brito says likely explains why the effect was best for men with mild ED.

He also points out that other studies used concentrations of 0.2 to 0.8 percent for patients with more severe ED, who likely needing higher concentrations.

In general, Brito says people prescribed nitroglycerin by their doctor should apply a small amount (pea-sized) to the head of the penis.

Side effects and contraindications

Nitroglycerin is certainly not for everyone. According to a 2018 review, taking nitroglycerin-based medications with certain PDE5 inhibitors like Viagra is contraindicated. Using them together can result in a sudden and serious decrease in blood pressure and potentially death.

According to Brito, some drawbacks of topical nitroglycerin include possible transmission to the partner, which can lead to the partner sharing in side effects, especially low blood pressure. This can lead to headache and nasal congestion.

Other treatments for ED

There are several treatments available for ED, including:

  • oral medications that include PDE5 inhibitors such as sildenafil (Viagra) and tadalafil (Cialis). Other oral medications include vardenafil HCL (Levitra), and avanafil (Stendra)
  • erectile dysfunction pump (penis or vacuum pump)
  • penile injections
  • inflatable penile prosthesis
  • psychotherapy (talk therapy) for emotional or psychological issues related to ED
  • suppositories (Alprostadil)
  • counseling
  • diet modifications
  • exercise
  • stress reduction

The takeaway

Although some research points to the effectiveness of nitroglycerin gel or cream for improving the symptoms of ED, it’s currently not approved by the FDA as a treatment for erectile dysfunction.

If you have ED or think you may have ED, it’s important that you talk with a doctor about any treatment options. They can talk with you about the range of options, including lifestyle modifications, counseling, oral agents, penis pumps, surgery, and implants.