An at-home DNA test promises to tell you what strain of weed is best for you, and what kind will make you paranoid

Many people swear off weed after taking too much of an edible on one occasion. Ending up anxiously couch-locked is no one’s idea of a good time, but what if there was a test to tell you a better way to get high?

This article is a repost which originally appeared on Insider
Andrea Michelson - October 4, 2021
Edited for content and readability Images sourced from Pexels
  • Endocanna Health offers a DNA test that tells you how to use cannabis better.
  • The analysis looks at genetic hallmarks that may influence how you respond to drugs.
  • With those genes in mind, the company says it can recommend a personalized profile.

Endocanna Health is offering a DNA test that claims to do just that for $199. Its team of scientists have identified 57 genetic signatures that may influence someone’s response to cannabis. From there, the company can recommend certain doses or formulations of cannabis for a customer’s specific needs.

Users can swab themselves at home with an Endo·dna test kit or send in data from another service like 23andMe for a smaller fee.

The company markets itself as “the future of personalized cannabinoid therapeutics,” founded with precision medicine in mind. Other companies such as HaluGen have created similar tests that screen for sensitivity to ketamine, mushrooms, and other psychedelics that are now being used for therapeutic purposes.

Your genetics affect how you respond to drugs

The Endocanna test considers a person’s response to THC, the compound in cannabis that’s associated with the high, along with the other parts of the plant. While some people feel relaxed or giddy after consuming THC, approximately 31% of the general population has reported an adverse reaction to the drug, according to Endocanna.

Studies have hinted at a genetic basis for how people respond to drugs: whether they’re predisposed towards anxiety and psychosis, or if they might have a greater tendency to become addicted.

Scientists haven’t identified a specific piece of genetic code that predicts a bad trip, but they have named some genes of interest. The AKT1 gene, for one, has a variant that’s been potentially linked to a higher risk of psychosis in people who use cannabis.

Other genes may be connected to unhealthy use of cannabis and other drugs. The National Institute on Drug Abuse estimates that 30% of people who use cannabis do so problematically, with some cases qualified as addiction. The gene CHRNA2 has also caught scientists’ interest as a potential factor in cannabis use disorder.

The test might tell you to avoid THC completely, or opt for a cannabis strain with higher levels of CBD, another cannabinoid that won’t get you high. Someone who tends to get anxious when using weed might opt for a high CBD to THC ratio for pain relief without the psychoactive risks.

Endocanna also says it considers terpenes, another type of cannabis compound that may affect the brain, when creating a personalized cannabis profile based on genetic information.

Ask a Stoner: Do Marijuana Sex Products Really Work?

Ask a Stoner: Do Marijuana Sex Products Really Work?

By Herbert Fuego

* This article is a repost which originally appeared on Westword

Dear Stoner: Can these marijuana sex products really help? I’ve seen some weird-looking shit at dispensaries.

Dear Krafty: Haven’t we all? If you can put it in your body, chances are good that someone’s tried to put weed in it first — and don’t even get us started on where CBD is being introduced. But we’ll limit our answer to the birds and the bees.

Sexual enhancement and pleasure products have indeed invaded dispensaries and the hemp industry, with pills, lubes and even suppositories infused with cannabis offered to allegedly ease sexual anxiety or pain in our privates, or just make us better at sex.

We can’t tell you from experience whether CBD lube really does ease vaginal pain from menstrual issues or during sex, or if THC or CBD anal suppositories “enhance erotic play,” as their maker, Foria, says they do.

We also don’t have experience with THC-infused herbal male enhancement pills, like CannaMojo, which claims to be an aphrodisiac. Reviews online go both ways, but I get enough stoner jokes as it is, so I prefer to buy my lube at a Walmart self-checkout with my head down. Like a real man.