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That's not true. I was on a 0 carb diet for months so my glycogen was basically non-existent and I still managed to lift really heavy in the gym 6 times a week and do 45 minutes of cardio every morning. The body is good at using fat for energy, that's why it's the tissue is choose to store - in order to use for energy later. If we didn't have this ability humans wouldn't be alive today.
I wasn't saying that once you deplete it, it's NEVER replenished, but if you ran for a while and you depleted everything and you need to run again, you're gonna be much less efficient. ALso, carbs are only macronutrients that body can go without.

