Random Show with Kevin Rose: Fasting, Biohacking, and Tony Robbins

Intro
  • This is another episode of The Random Show – what Tim and Kevin call their periodic podcasts together
  • Kevin is best known for creating Digg
  • Kevin and Tim have co-invested in about a dozen or so deals – Facebook, Twitter, Blue Bottle Coffee
    • Blue Bottle was acquired by Nestle for around $700 million
  • Kevin and Tim met at Tim’s launch party for his book, The 4-Hour Work Week
    • Tim held a boat party on the SS Jeremiah on the San Francisco Bay
The Fasting Mimicking Diet (FMD)

  • What does a FMD entail?
    • 5 days of eating low protein, low sugar, vegan, lots of good fat (about 700 calories a day in total) – repeated monthly (or less) depending on the need
  • How does the FMD differ from a water only fast?
    • The compliance of doing a 5 day water only fast is pretty low
    • As mentioned, with the FMD, you are allowed to consume about 700 calories per day, for 5 days
    • Kevin estimates that he still does get into ketosis while doing a FMD, between his eating periods
  • What do you eat on the FMD?
    • You can order food premade for the diet from Dr. Longo’s nonprofit, Prolon – the money made goes back into research
      • The Prolon kit consists of a few snacks which you eat throughout the course of a day
  • The benefits of a FMD
    • Some autophagy (damaged cell death)
    • Some stem cell production 
    • It lowers LDL cholesterol, raises HDL cholesterol – both of which are an improvement
  • How often do you do a FMD?
    • When first starting – once a month for three months, and then once a quarter after that
  • Through many conversations with Dr. Dom D’Agostino, Tim has come to learn that fasting prior to chemotherapy and radiation has the potential to increase the resilience of normal (healthy) cells, while increasing the susceptibility of the cancer cells to the chemotherapy drug
    • Tim and Kevin discuss a friend who would do a water only fast for 3 days before his chemotherapy treatments – this would allow him to feel totally normal the day following the chemotherapy
    • By fasting – you’re depriving the cancer cells of sugar and glucose, which makes them more susceptible to the treatment
  • Dr. Peter Attia has created his own version of the FMD
    • In his protocol, the food you eat consists of much more dietary fat so you remain in ketosis
    • His protocol involves eating only 1 small meal a day – it’s a small salad with greens, 3-4 tbsp of olive oil, some olives, and seeds
  • Both Tim and Kevin use the Precision Xtra to measure their blood ketone levels
What has changed for Kevin since having a daughter?
  • His daughter’s name is Zelda, she’s 4 months old
    • Both Kevin and his wife love the Zelda game
  • “It changes the way I want to approach life in terms of which things are important. I try to make more time to be a good father.”
Minimalism
  • Kevin is trying to live more of a minimalist lifestyle
    • He recently implemented a personal rule – he has to throw away or donate something every day
    • By taking the minimalism process day by day, Kevin doesn’t find himself getting overwhelmed
    • “For the least amount of burden, and the most happiness, just have less stuff”
  • For more on minimalism, check out the book The Life-Changing Magic of Tidying Up
    • Note from Podcast Notes – READ THIS
  • If you come across something you want to buy on Amazon, Kevin has a cool trick
    • Set the product in the ‘save for later’ section
    • Set a reminder in your calendar app. for 1-2 weeks later to remind yourself to check back on it
    • You’ll often find that after 1-2 weeks, you really don’t want the item as much
Supplements and Diet
  • Kevin recently tried taking 200mg of l-theanine with coffee
  • Tim first experimented with taking NAC (N-Acetyl Cysteine) as a means to accelerate recovery between workouts
    • NAC is a precursor to glutathione which is a “master antioxidant” – he thought this would aid in the recovery
    • Tim noticed that after 7-8 days, he was more “even-keeled”
    • After examining PubMed – he discovered there were a number of search results that seemed to indicate there was some promise in using NAC to mitigate the amplitude of the ups and down associated with bipolar disorder
  • Tim has been taking 5mg of Lithium Orotate daily
  • “Use supplements as supplements. Do not use them to absorb you of the responsibility of eating proper food.”
  • Tim judges his baseline state in two ways
    • How he feels when he wakes up
      • Does he want to stay in bed because he doesn’t want to face the day? Is he anxious? Are these his first thoughts coming out of bed?
    • How much trouble he has sleeping
      • In addition, how much deep+REM sleep he gets
      • To monitor how well you sleep check out the Oura Ring
        • Use the code “podcastnotes” at checkout for $50 off your order
      • Tim has noticed that while in deep ketosis, he needs much less sleep (6 vs. 8 hours), and feels much better upon waking
  • What does Kevin track?
    • His waking glucose, bedtime glucose, how many hours he’s fasted the night prior, whether he meditated or not that day, how many drinks he’s had that day, if he worked out, whether he had tea/coffee, and what he ate (not a calorie count, but more so just the type of food he’s eaten)
    • “Just the act of writing it down, makes me behave a little better”
Alcohol
  • What has helped Kevin to lessen the amount of alcohol he consumes?
    • There’s been a few studies published recently linking dementia and alcohol abuse
    • He wants to live longer now that he has a daughter
    • Getting older – “Hangovers happen after 2.5 drinks these days”
    • Also the sauna
      • Using the sauna has helped Kevin replace the need to drink
  • How does Kevin reduce the temptation to drink in social settings?
    • As we all know, alcohol is a good social lubricant
    • “You’ll never become more comfortable in new interactions and breaking the ice, if you always go to the booze”
    • Think of the social setting as a workout for your introvert muscle
    • Another tip – show up late, so you skip a drink
  • What does Tim do?
    • If you don’t want to drink, and people are pressuring you, just say – “I’m on a bunch of weird drugs, I can’t mix them with alcohol”
      • You aren’t even supposed to mix Tylenol and alcohol
    • Just drink club soda with a splash of cranberry juice 
      • This looks like an alcoholic drink, so it fools people
  • Tim sometimes does drunk dial podcasts
    • He’ll drink and call his listeners to answer their questions
    • Check out our Podcast Notes from his latest
Learning
  • Kevin is in the middle of the course Learning How To Learn on Coursera
    • It’s pretty popular
    • Check out our Podcast Notes from this cool episode of The Art of Manliness – Learning How to Learn
  • Tim has noticed the following improves his learning:
    • Studying the material right before bed
    • When you wake up, before doing anything else, do a recall exercise (Tim uses flash cards)
    • Check out the book Spark: The Revolutionary New Science of Exercise and the Brain, which discusses the role of exercise in education and learning
      • Tim has noticed that exercise, mainly resistance training, does have a positive impact on learning
      • Also check out the book Body by Science
  • When you see scientific claims in the news, a good question to ask – “What else might explain this?”
Tony Robbins
  • Tim has done both the  Unleash the Power Within (UTPW) and Date with Destiny events with Tony Robbins
    • The I Am Not Your Guru documentary on Netflix showcases much of what the Date with Destiny event looks like
  • Kevin did the UTPW event recently and loved it
    • “Everyone, if they’re honest with themselves, has something they’re trying to work on”
    • As a part of the event, you walk over hot coals
  • Tim’s take:
    • The exercises that have an impact on you, may be completely different from the exercises that have a large impact on someone else
    • “When you go to an event like this, be skeptical, not cynical, and open to trying all these exercises that Tony suggests”
    • Most likely
      • You’ll find 20% of the exercises uncomfortable and you’ll strongly dislike them
      • You’ll discard 60% of them
      • For 10-25% of the exercises, you’ll go “Holy shit, I can’t believe how powerful that just was”
    • “Tony knows his shit”
  • Kevin – “He knows how to set up these traps, that trick you into re-framing things in your mind, and it really does change your long term perspective on things”
  • “It’s not easy, it’s not comfortable, but I benefited from attending” – Tim
    • “With particular types of self imposed narratives and handicaps that you’ve built yourself, or walls around certain types of thinking or emotions, that perhaps served you very well in the past, but no longer serve you, he is exceptionally good at helping you work through all of that”
  • The self-help industry is booming, and becoming much more accepted
    • “Everyone now has access to expertise that even 10 years ago would have cost hundreds of thousands of dollars to access”

*This article is a repost which originally appeared on the Podcast Notes Website.

The Biohacking Emperor of Self-Quantification

Quantified Bob (Bob Troia) is a legend in the biohacking industry, and someone who is known as the king of self-experimentation, data gathering, and biohacking the human body in the way that very few people can claim. More than anything, Bob is known for self-quantification, which is the process of cataloguing information about certain biomarkers, and using that information to improve his mind and body.
In this interview, we discuss some of the most surprising things Bob has uncovered in his journey as a biohacker, some of the most profound things he’s discovered when it comes to controlling his biology, extremely powerful hacks for sleep, uncovering the truth about grounding (or earthing as it’s sometimes known), simple biohacks almost anyone can do, modalities of treatment or healing that didn’t work for him, advice for new biohackers, and so much more.
I thoroughly recommend searching for more information about Bob, as well as following his adventures in the world of self-quantification, which you can do via http://quantifiedbob.com/ or by doing a simple Google search on the man himself.
I hope you enjoy. Feel free to share this episode around if you received some value out of it, and I look forward to sharing more like this in the future.

CONNECT
Connect with Leon The Alchemist online for more intensive biohacking, longevity, and performance advice daily, with exclusive content you won’t find anywhere else:
INSTAGRAM: @LeonTheAlchemist | https://www.instagram.com/leonthealchemist
TWITTER: @AlchemistLeon | https://twitter.com/alchemistleon
LINKTREE: https://linktr.ee/leonthealchemist
WEBSITE: http://bioalchemy.co
COURSE: http://bio.ax/

 

*This article is a repost which originally appeared on the Bio Alchemy Website.

 

The Keys to Longevity with Peter Attia

In this episode of Revolution Health Radio (RHR) we discuss “RHR: The Keys to Longevity with Peter Attia.” Peter Attia and I discuss eight levers that influence one’s longevity, the commonalities of degenerative diseases, and the importance of social support and sense of purpose when it comes to your health.
In this episode, we cover: Peter’s approach to longevity Commonalities of degenerative diseases Social support and sense of purpose

READ FULL ARTICLE: http://chriskresser.com/the-keys-to-l…
Chris Kresser, M.S., L.Ac, is a practitioner of integrative and functional medicine, the creator of one of the world’s most respected natural health sites, ChrisKresser.com, and author of the New York Times best seller, Your Personal Paleo Code. He is widely known for his in-depth research uncovering myths and misconceptions in modern medicine and providing natural health solutions with proven results.
The Revolution Health Radio Show is brought to you by ChrisKresser.com and http://14Four.me.

 

*This article is a repost which originally appeared on the Revolution Health Radio YouTube.

Dr. Peter Attia on Longevity Compounds, Fasting, Supplements and More

Key Takeaways:
  • “If you look at the administration of rapamycin across about a billion years worth of evolutionary animal models, everything from yeast to worms, fruit flies to mammals (mice and dogs), this compound seems to universally increase life”.
  • Rapamycin binds to a complex, called mTOR (mechanistic target of rapamycin) in our cells and inhibits its function.
  • mTOR regulates autophagy
    • When mTOR activity is turned down (by taking rapamycin), the body is more likely to undergo autophagy.
      • Autophagy is the process by which cells eat themselves – the dysfunctional cells (like cancer cells) tend to be “eaten” first.
    • In a sense – the inhibition of mTOR mimics what happens to the body in a nutrient sparse environment.
  • Peter has been taking 5 mg of rapamycin for the last 3 months (he doesn’t specify how often, but it sounds like every 4-7 days).
  • We can also suppress mTOR by fasting.
  • Peter does a 1 week water only fast once per quarter, sandwiched on both sides by a week of following a ketogenic diet.
    • “I think it’s really important to lift weights while fasting, because it really holds off the muscle mass loss”
Cool Products and Supplements Mentioned:
  • Peter only trusts two branched-chain amino acid (BCAA) companies – Ajinomoto and Biosteel
  • “I think there’s really some pretty good data on curcumin’s antinflammatory benefits, and in particular some much more compelling data on a formulation of it called Theracumin
  • Peter takes Kirk Parsley’s Sleep Cocktail (a double dose) to help him fall asleep on planes
    • He’s mentioned on other podcasts that he takes it every night before bed as well.
*This article is a repost which originally appeared on the Podcast Notes Website.

 

Ben Greenfield and Kyle Kingsbury on Smart Drugs, Nootropics, Microdosing With Psychedelics, Enhancing Deep Sleep & Much More

Listen to this podcast on the BENGREENFIELDFITNESS with Ben Greenfield and Kyle Kingsbury.
“Recently, I had the chance to sit down at Onnit with my friend and the host of the Human Optimization Hour podcast, Kyle Kingsbury. During our discussion, we delve into a host of topics including the latest and greatest on smart drugs, nootropics, and psychedelic micro-dosing, deep sleep enhancement, rites of passage and much more!”

In my conversation with Kyle, you’ll discover:

-What Ben does to optimize his sleep…6:42

-Optimizing psychedelics for performance…24:37

  • Ketamine (recalling previous traumatic experiences)
    • Intranasal ketamine
    • Ben’s wife had difficulty with learning
    • Ben can recall his childhood in vivid detail; connects with his boys
  • Microdose psilocybin
    • Ben doesn’t like to lose control of his cognitive function
    • Use during nature experiences: hiking, hunting, etc.
  • Lysergi
    • Amplifies dopamine levels (beware of overdosing)
  • If legality is an issue:

-Ben’s thoughts on the efficacy of Restore for healing leaky gut…37:00

  • Seals leaky gut based on its interaction with the zonulin protein
  • Mitigates issues brought on by glyphosate exposure
  • Ben and his family use it regularly

-Ben’s preferred sources for colostrum…40:20

-Rites of passage and thoughts on how we’re raising our boys in modern American culture…44:00

-And much more…

Click here for the full written transcript of this podcast episode.

This was originally published in BENGREENFIELDFITNESS by Ben Greenfield. This is a repost. See the original post here.

 

Ray Kurzweil on what the future holds next

From A TED Original Podcast
Join head of TED Chris Anderson for a very special conversation with legendary inventor and computer scientist Ray Kurzweil, recorded live onstage at TED2018. Listen in to hear what the man who makes a living from predicting the future arc of technology thinks is coming our way next — including a specific prediction of when he thinks technology will finally gain human levels of language understanding.
ABOUT THE SPEAKERS
Ray Kurzweil · Inventor, futurist
Ray Kurzweil is an engineer who has radically advanced the fields of speech, text and audio technology. He’s revered for his dizzying — yet convincing — writing on the advance of technology, the limits of biology and the future of the human species.
Chris Anderson · Head of TED
After a long career in journalism and publishing, Chris Anderson became the curator of the TED Conference in 2002 and has developed it as a platform for identifying and disseminating ideas worth spreading.

 

Episode 66: Living to 156 Years – Exponential Wisdom Podcast

Exponential Wisdom Living to 156
Listen to this episode on the Exponential Wisdom Podcast with Peter Diamandis and Dan Sullivan.

Peter and Dan discuss Dan’s new book,
“My Plan for Living to 156,” and their shared belief that mindset is critical to longevity. You’ll hear about one of the book’s key themes — “everyone’s got a number” — and learn why a longevity goal is extremely important in enabling a long, healthy lifespan.

In this episode:
  • Dan gives his biggest takeaways from the book (pick up your copy here), starting with a special tool he calls “The Lifetime Extender” and an idea to eliminate retirement.
  • Peter discusses why purpose is fundamental to longevity, and why humans are purpose-driven animals.
  • Dan and Peter describe your mindset as a skill like a muscle; just as you’d go to the gym to build muscle, you must always train your mindset. Reinventing who you are in the present when new technology comes online is critical for a happy, long life.

Subscribe to the Exponential Wisdom Podcast:

Subscribe via Apple podcasts

Subscribe via AndroidSubscribe via RSS

This was originally published in Exponential Wisdom by Peter Diamandis. This is a repost. See the original post here.

 

My Plan for Living to 156 book Dan Sullivan

Download a free copy of Dan Sullivan’s ebook, My Plan For Living To 156,’ plus audio interviews, a scorecard tool, video synopses, and more. Get it now!

Harnessing Autonomic Arousal to Think & Do Better – Andrew Huberman #572

Listen to the podcast at on Bulletproof Radio.

In this episode of Bulletproof Radio, we talk about how you can increase cognitive capacity by leveraging your stress; how the brain is wired for fear; advances in virtual reality; and why a daily dose of real brain science on Instagram is good for just about everyone.

My guest is neuroscientist Andrew Huberman, Ph.D. He studies comparative neurology to better understand the human brain and human brain evolution. He’s also working to make neuroscience more accessible and relevant to people’s everyday life. And he’s in a particularly good position to do just that at Stanford School of Medicine where he’s an associate professor in the Department of Neurobiology and the Department of Ophthalmology. His own Huberman Lab performs clinical trials using molecular, genetic, physiological and virtual reality tools.

His work includes developing ways to regenerate the brain after injury and in neurodegenerative disorders, mainly those causing blindness. Another aspect of his research parses the mechanisms for stress, “courage” (adaptive action toward potential threats), and testing treatments and protocols for anxiety disorders and trauma.

Dr. Huberman has made numerous—and award-winning– contributions to the fields of brain development, brain plasticity, and neural regeneration and repair.

Enjoy the show!

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This was originally published in https://blog.bulletproof.com. This is a repost. See the original post here.

The Nervous System Circuitry of Safety, Sound & Gratitude – Stephen Porges #573

Listen to the podcast at on Bulletproof Radio.

Bulletproof Radio welcomes scientist Dr. Stephen Porges back to the show. He’s known for his deep and profound understanding of the human nervous system and its application to real-life clinical settings.

Dr. Porges created the Polyvagal Theory, which explains the workings of the vagal nerve and links the evolution of the mammalian autonomic nervous system to social behavior. He has authored and co-authored several books on the subject. For 25 years, his Polyvagal Theory has been leading to innovative treatments based on insights into the mechanisms mediating symptoms observed in behavioral, psychiatric, and physical disorders.

One of my favorite episodes of Bulletproof Radio was #264 when he and I talked about this theory. I encourage you to listen to that episode and check out the two Bulletproof Blog articles. I was so impressed with his research that I included it in my new book Game Changers, specifically Law #44, which is “Gratitude is Stronger than Fear.”

Dr. Porges also is the creator of a music-based intervention, the Safe and Sound Protocol™, which currently is used by more than 1200 therapists to improve spontaneous social engagement, to reduce hearing sensitivities, and to improve language processing, state regulation, and spontaneous social engagement.

In this new episode, we explore how sound, safety, environment and gratitude are all intimately connected to our nervous system circuitry.

“Your body, in safe environments, will start to spontaneously optimize those circuits,” explains Dr. Porges. “We need to structure narratives that have a degree of positivity, so that our nervous system doesn’t feel too scared to evaluate it.”

We’ll be making links between Dr. Stephen’s work and fascinating brain-body interactions, often deeply rooted in our ancient biology. We introduce “neuroception,” find out how to structure environments for those who struggle with sensory processing issues, better understand how hearing frequencies affect adults and kids differently, and learn how to control our own heart rate variability.

Enjoy the show!

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This was originally published in https://blog.bulletproof.com. This is a repost. See the original post here.

Up-level Your Approach to Food – Izabella Wentz #571

Listen to the podcast at on Bulletproof Radio.

I care a lot about food, and I fundamentally think food is the single biggest tool you have to increase your performance, to change how you look, and to change how your brain works.

In this episode of Bulletproof Radio, I talk with Dr. Izabella Wentz, PharmD, an internationally acclaimed thyroid specialist and licensed pharmacist who has dedicated her career to addressing the root causes of autoimmune thyroid disease after being diagnosed with Hashimoto’s Thyroiditis in 2009. She also cares about food in the same way that I do. She developed the term “food pharmacology” to explain the profound effect that food has on our physiology and biology.

From her self-described “nerdy pharmacist” perspective, food works in ways similar to medication in the human body. She wants people to become their own food gurus and ask: “If I have this symptom, what do I need to modify? Is there a digestive enzyme that I need to take? Or is there a nutrient that can really up-level my response to nutrition?” Our conversation also touches on adaptive physiology, food sensitivities, mold and essential self-care.

She believes food can be a powerful ally in your healing journey. “My goal is to establish a communication pathway for people between their bodies and the things that they’re ingesting,” she says.

As a patient advocate, researcher, clinician, educator and also a best-selling author of two previous books and a new one publishing in March, she is committed to raising awareness on how to overcome autoimmune thyroid disease, how to use food as medicine, and how to manage the stresses and toxins in our everyday environments.

Enjoy the show!

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This was originally published in https://blog.bulletproof.com. This is a repost. See the original post here